AI Patient
Intelligence Engine
for Rare Disease.
One AI engine to find, engage, and understand rare disease patients.
Schedule a meeting with us
See how AI patient intelligence can move your program forward.
— Our Founders
Built by a
rare disease
family.
What started as our family's rare disease journey led us to build an AI Patient Intelligence Engine connecting 1M+ patients worldwide to new research, support, and industry partners.
1M+
Patient Reach
500+
Research Partners
Global Coverage
ISO 27001 Data Security
Therapeutic Coverage
One Patient Intelligence Engine.
Three Integrated AI Systems.
Continuously find, engage, and understand rare disease patients to better power research, development, and commercialization.
System 01
Find
HealthSignal
AI Patient Discovery
System 02
Engage
HealthStory
AI Patient Experience
System 03
Understand
HealthSense
AI Patient Insights
: System 01
HealthSignal
Find high-intent patients
through search behavior.
An AI engine that maps real-world search behavior, generates and tests tailored landing pages, and learns what surfaces the most relevant patients.
Search Intelligence
High-Intent Patients
12,400
surfaced through search behavior
Signal Quality
89%
of queries match engaged patients
Landing Page Tests
Variant A
2.3%
CTR
Variant B
5.8%
CTR
Variant C
3.1%
CTR
Winner · Variant B
+152% lift · auto-promoted
: System 02
HealthStory
Engage patients continuously
through everyday conversations.
AI-guided conversations keep patients engaged while capturing real-world insights on symptoms, treatments, and quality of life over time.
healthstoryai
Hi Jake, how have your headaches been this week?
Still pretty bad — worst in the mornings, and bright light makes them worse.
● Symptom Entry · Headaches
Severity ↑ · morning onset + photophobia trigger noted. Logged.
Symptom Breakdown
Episode Duration
: System 03
HealthSense
Understand patients better
through continuous intelligence.
Real-time patient intelligence powers smarter recruitment, deeper understanding, and more informed decisions for study protocols, market development, and commercialization.
Cohort · Pompe Disease
Real-Time Patient Intelligence
Patients in Cohort
0
Treatment Adherence
0%
New Entries / Wk
+0
Reported Symptom Drivers
Episodes / Wk
0
AI Insight
Sleep disruption precedes 64% of reported flares — a target for adherence support.
: Our Programs
Powering rare disease
from research to launch.
Integrated AI patient intelligence programs supporting recruitment, strategy, and commercialization.
Clinical Development Program
Accelerate recruitment
Medical Strategy Program
Understand patient experiences
Commercialization Program
Support launch & growth
: C A S E S T U D I E S
Real programs. Real outcomes.
See the results.
See how pharma and biotech teams have used Know Rare's AI Patient Intelligence Engine to accelerate recruitment and generate real-world evidence.
How AI Patient Intelligence Helped Rescue a Rare Pediatric Trial.
How AI Patient Intelligence Helped provide a deeper understanding of pain management.
Power your rare disease work
with AI patient intelligence.
See how rare disease intelligence can move your program forward.
1M+
Patient
Reach
500+
Research
Partners
Global
Coverage
ISO 27001
Data Security
Schedule a meeting with us
See how AI patient intelligence can move your program forward.